Wilsons fame was surpassed by the U.S. in 2014 after she was cast on Showtimes The Affair. In the show, Wilson played Alison Lockhart who is a young woman who is troubled and comes who comes from a rough background. Lockhart falls for a married Noah Solloway. Wilson received a Golden Globe Award for Best Actress in a Television Series in Drama 2015 together with Mauratierney as well as Joshua Jackson. Wilson told British Vogue: "I love the fact that I am able to play characters in two perspectives." Noah sees Alison to be this attractive, sexy and confident character. She sees herself in a totally different way which appears to be dowdy as well as in the shadows, not wanting to stand out. Wilson also stated that she believed America is morally skewed. Wilson, who left The Simpsons in the year 2018, was not forthcoming with details. In an interview with CBS This Morning in August, on CBS This Morning, Wilson stated that she did wish to leave the show but was not permitted to